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Krivic, A., Majerovic, M., Jelic, I., Seiwerth, S., & Sikiric, P

Proc Natl Acad Sci U S A 105:1460914614 Thomas Dickey D, Muldoon LL, Kraemer DF, Neuwelt EA (2004) Protection against cisplatin-induced ototoxicity by N-acetylcysteine in a rat model

Chemical modifications implemented with nucleotides or the phosphate backbone can reduce off-target binding and immune stimulation

As the FOXO proteins are regulated by SGK1 and Akt, SGK can be the mTORC2 effector, whereas Akt appears to be a more subtle modulator (Liu and Sabatini, 2020a